Background:

This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.

Applications:

ELISA, IHC

Name of antibody:

PDE5A

Immunogen:

Synthetic peptide of human PDE5A

Full name:

phosphodiesterase 5A, cGMP-specific

Synonyms：

CN5A; PDE5; CGB-PDE

SwissProt:

O76074

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human thyroid cancer and Human breast cancer

IHC Recommend dilution:

100-300