Background:

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias.

Applications:

ELISA, IHC

Name of antibody:

NUP88

Immunogen:

Synthetic peptide of human NUP88

Full name:

nucleoporin 88kDa

SwissProt:

Q99567

ELISA Recommended dilution:

500-1000

IHC positive control:

Human colorectal cancer

IHC Recommend dilution:

25-100