Background:

This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3.

Applications:

ELISA, IHC

Name of antibody:

PROS1

Immunogen:

Fusion protein of human PROS1

Full name:

protein S (alpha)

Synonyms：

PSA; PROS; PS21; PS22; PS23; PS24; PS25; THPH5; THPH6

SwissProt:

P07225

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human cervical cancer and human thyroid cancer

IHC Recommend dilution:

50-200