Background:

Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake.

Applications:

ELISA, WB, IHC

Name of antibody:

STARD5

Immunogen:

Synthetic peptide of human STARD5

Full name:

StAR-related lipid transfer (START) domain containing 5

SwissProt:

Q9NSY2

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human breast cancer

IHC Recommend dilution:

40-150

WB Predicted band size:

24 kDa

WB Positive control:

Human fetal brain tissue

WB Recommended dilution:

500-2000