Background:

The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13.

Applications:

ELISA, WB, IHC

Name of antibody:

STAR

Immunogen:

Fusion protein of human STAR

Full name:

steroidogenic acute regulatory protein

Synonyms：

STARD1

SwissProt:

P49675

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human lung cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

32 kDa

WB Positive control:

231 cells

WB Recommended dilution:

200-1000