Background:

The protein involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of FATP1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids .Highest levels of expression are detected in muscle and adipose tissue small, intermediate levels in small intestine, and barely detectable in liver.

Applications:

ELISA, IHC

Name of antibody:

SLC27A1

Immunogen:

Synthetic peptide of human SLC27A1

Full name:

solute carrier family 27 (fatty acid transporter), member 1

Synonyms：

FATP; FATP1; ACSVL5

SwissProt:

Q6PCB7

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human esophagus cancer and Human lung cancer

IHC Recommend dilution:

50-200