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Background:
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
Applications:
ELISA, WB, IHC
Name of antibody:
TNFSF13B
Immunogen:
Fusion protein of human TNFSF13B
Full name:
tumor necrosis factor (ligand) superfamily, member 13b
Synonyms:
DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNFSF20
SwissProt:
Q9Y275
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human liver cancer and human lymphoma
IHC Recommend dilution:
25-100
WB Predicted band size:
31 kDa
WB Positive control:
K562, 231 and SKOV3 cells
WB Recommended dilution:
200-1000