Background:

The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain, a RING-type zinc finger, and two TRAF-type zinc fingers. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. Alternate transcriptional splice variants have been characterized.

Applications:

ELISA, WB, IHC

Name of antibody:

TRAF5

Immunogen:

Fusion protein of human TRAF5

Full name:

TNF receptor-associated factor 5

Synonyms：

RNF84; MGC:39780

SwissProt:

O00463

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human lung cancer and human thyroid cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

64 kDa

WB Positive control:

Jurkat cells

WB Recommended dilution:

500-2000