Background:

This nuclear gene encodes a mitochondrial protein tyrosine aminotransferase which is present in the liver and catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate. Mutations in this gene cause tyrosinemia (type II, Richner-Hanhart syndrome), a disorder accompanied by major skin and corneal lesions, with possible mental retardation. A regulator gene for tyrosine aminotransferase is X-linked.

Applications:

ELISA, WB, IHC

Name of antibody:

TAT

Immunogen:

Fusion protein of human TAT

Full name:

tyrosine aminotransferase

SwissProt:

P17735

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human colon cancer and Human liver cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

50 kDa

WB Positive control:

Human normal liver tissue

WB Recommended dilution:

200-1000