Background:

Transmembrane 7 superfamily member 2 (TM7SF2, Sterol C14-reductase, 3beta-hydroxysterol Delta-reductase) is a 418 amino acid gene product that belongs to the ERG4/ERG24 family. TM7SF2 is a seven pass transmembrane protein that can localize to the membrane of the endoplasmic reticulum. TM7SF2 is involved in the conversion of lanosterol to cholesterol and, specifically, catalyzes the NADPH dependant reduction of 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol to 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol and NADP+.

Applications:

ELISA, WB, IHC

Name of antibody:

TM7SF2

Immunogen:

Synthetic peptide of human TM7SF2

Full name:

transmembrane 7 superfamily member 2

Synonyms：

ANG1; NET47; DHCR14A

SwissProt:

O76062

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

46 kDa

WB Positive control:

Human fetal brain tissue

WB Recommended dilution:

500-2000