Background:

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.

Applications:

ELISA, IHC

Name of antibody:

MAP3K10

Immunogen:

Synthetic peptide of humanMAP3K10

Full name:

mitogen-activated protein kinase kinase kinase 10

Synonyms：

MST; MLK2; MEKK10

SwissProt:

Q02779

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

25-100