Background:

This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

SLC25A13

Immunogen:

Fusion protein of human SLC25A13

Full name:

solute carrier family 25 (aspartate/glutamate carrier), member 13

Synonyms：

CTLN2; CITRIN; ARALAR2

SwissProt:

Q9UJS0

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and human liver cancer

IHC Recommend dilution:

25-100

WB Recommended dilution:

500-2000

WB Positive control:

Hepg2, A172 and Raji cells

WB Predicted band size:

74 kDa