Background:

This gene encodes a member of a family of cysteine- and proline-rich proteins. The encoded protein is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. Activity of this protein impairs the formation of active GTP-RAS. Nucleotide variation in this gene has been associated with hypogonadotropic hypogonadism 17 with or without anosmia. Alternative splicing results in a multiple transcript variants.

Applications:

ELISA, WB, IHC

Name of antibody:

SPRY4

Immunogen:

Full length fusion protein

Full name:

sprouty RTK signaling antagonist 4

Synonyms：

HH17

SwissProt:

Q9C004

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human lung cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

33 kDa

WB Positive control:

K562，A375 and 231 cell

WB Recommended dilution:

500-2000