Background:

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Applications:

WB

Name of antibody:

SYK(Phospho-Tyr352)

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 352(S-P-Y(p)-A-D) derived from Human SYK.

Full name:

spleen tyrosine kinase

Synonyms：

p72-Syk

SwissProt:

P43405

WB Predicted band size:

72 kDa

WB Positive control:

Huvec cells and HepG2 cells lysates

WB Recommended dilution:

500-1000