Background:

The protein encoded by this gene localizes to the primary cilium and to the plasma membrane. The gene functions in centriole migration to the apical membrane and formation of the primary cilium. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Meckel syndrome type 3 (MKS3) and Joubert syndrome type 6 (JBTS6).

Applications:

ELISA, WB, IHC

Name of antibody:

TMEM67

Immunogen:

Fusion protein of human TMEM67

Full name:

transmembrane protein 67

Synonyms:

MKS3; JBTS6; NPHP11; TNEM67; MECKELIN

SwissProt:

Q5HYA8

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and Human brain

IHC Recommend dilution:

20-100

WB Predicted band size:

112 kDa

WB Positive control:

Human kidney tissue and A549 cell lysates

WB Recommended dilution:

200-1000