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Background:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2.
Applications:
ELISA, WB
Name of antibody:
TAP2
Immunogen:
Synthetic peptide of human TAP2
Full name:
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Synonyms:
APT2; PSF2; ABC18; ABCB3; PSF-2; RING11; D6S217E
SwissProt:
Q03519
ELISA Recommended dilution:
1000-2000
WB Predicted band size:
76 kDa
WB Positive control:
Jurkat cells
WB Recommended dilution:
200-1000