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Background:
Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs; a coiled-coil (leucine zipper) motif; and a homologous region that defines the TRAF family, the TRAF domain, which is involved in self-association and receptor binding.
Applications:
ELISA, WB, IHC
Name of antibody:
TRAF7
Immunogen:
Synthetic peptide of human TRAF7
Full name:
TNF receptor-associated factor 7, E3 ubiquitin protein ligase
Synonyms:
RFWD1, RNF119
SwissProt:
Q6Q0C0
ELISA Recommended dilution:
1000-5000
IHC positive control:
Human colon cancer and Human gastric cancer
IHC Recommend dilution:
15-50
WB Predicted band size:
67 kDa
WB Positive control:
Jurkat cells
WB Recommended dilution:
200-1000