Background:

This gene encodes a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. The encoded protein may play a role as an intrinsic regulator of the self-renewal capacity of germline and hematopoietic stem cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

PIWIL1

Immunogen:

Fusion protein of human PIWIL1

Full name:

piwi-like RNA-mediated gene silencing 1

Synonyms：

HIWI, MIWI, PIWI

SwissProt:

Q96J94

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human colon cancer and human esophagus cancer

IHC Recommend dilution:

25-100