Background:

This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.

Applications:

WB, IHC

Name of antibody:

RUVBL2

Immunogen:

Fusion protein of human RUVBL2

Full name:

RuvB-like AAA ATPase 2

Synonyms：

RVB2; TIH2; ECP51; TIP48; CGI-46; INO80J; REPTIN; TIP49B

SwissProt:

Q9Y230

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

51 kDa

WB Positive control:

K562, hela, Jurkat and 293T cell

WB Recommended dilution:

500-2000