Background:

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.

Applications:

ELISA, IHC

Name of antibody:

S100A1

Immunogen:

Fusion protein of human S100A1

Full name:

S100 calcium binding protein A1

Synonyms：

S100; S100A; S100-alpha

SwissProt:

P23297

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and human ovarian cancer

IHC Recommend dilution:

25-100