Background:

This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.

Applications:

ELISA, IHC

Name of antibody:

PODXL

Immunogen:

Synthetic peptide of human PODXL

Full name:

Podocalyxin-like

Synonyms：

PC, PCLP, Gp200, PCLP-1

SwissProt:

O00592

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human colon cancer and Human ovarian cancer

IHC Recommend dilution:

25-100