Background:

The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated with heparin cofactor II deficiency.

Applications:

IHC, IF

Name of antibody:

SERPIND1

Immunogen:

Synthesized peptide derived from internal of human Heparin Cofactor II.

Full name:

serpin peptidase inhibitor, clade D (heparin cofactor), member 1

Synonyms：

HC2; LS2; HCF2; HCII; HLS2; THPH10; D22S673

SwissProt:

P05546

IHC positive control:

Human liver carcinoma tissue

IHC Recommend dilution:

50-100

IF positive control:

HepG2 cells

IF Recommend dilution:

100-500