Background:

This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

Applications:

ELISA, IHC

Name of antibody:

MAP4K5

Immunogen:

Fusion protein of human MAP4K5

Full name:

mitogen-activated protein kinase kinase kinase kinase

Synonyms：

KHS; GCKR; KHS1; MAPKKKK5

SwissProt:

Q9Y4K4

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human ovarian cancer and human thyroid cancer

IHC Recommend dilution:

15-50