Background:

Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage.

Applications:

ELISA, WB, IHC

Name of antibody:

MSN

Immunogen:

Fusion protein of human MSN

Full name:

moesin

SwissProt:

P26038

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and Human ovarian cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

68 kDa

WB Positive control:

293T and A431 cells

WB Recommended dilution:

500-2000