Background:

This gene encodes an adapter protein that contains three N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants.

Applications:

ELISA, WB, IHC

Name of antibody:

SH3KBP1

Immunogen:

Fusion protein of human SH3KBP1

Full name:

SH3-domain kinase binding protein 1

Synonyms：

HSB1; CIN85; GIG10; HSB-1; MIG18; CD2BP3

SwissProt:

Q96B97

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and human breast cancer

IHC Recommend dilution:

30-150

WB Predicted band size:

73 kDa

WB Positive control:

Jurkat cells

WB Recommended dilution:

500-2000