Background:

This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.

Applications:

WB

Name of antibody:

SF3B6

Immunogen:

Synthesized peptide derived from C-terminal of human SF3B14.

Full name:

splicing factor 3b, subunit 6, 14kDa

Synonyms：

P14; Ht006; SAP14; SAP14a; SF3B14; CGI-110; HSPC175; SF3B14a

SwissProt:

Q9Y3B4

WB Predicted band size:

15 kDa

WB Positive control:

HepG2 cells lysate

WB Recommended dilution:

500-3000