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英文名稱： ZFP36 Antigen (Recombinant Protein)
別 名： ZFP36 ring finger protein; TTP; G0S24; GOS24; TIS11; NUP475; zfp-36; RNF162A
相關(guān)類別： 抗原
儲(chǔ) 存： 冷凍（-20℃）
概述
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Fusion protein corresponding to a region derived from 127-326 amino acids of human ZFP36 |
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Full name: |
ZFP36 ring finger protein |
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Synonyms: |
TTP; G0S24; GOS24; TIS11; NUP475; zfp-36; RNF162A |
|
Swissprot: |
P26651 |
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Gene Accession: |
BC009693 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Recruits deadenylase CNOT7 (and probably the CCR4-NOT complex) via association with CNOT1. Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF). Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF). |
