Background:

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).

Applications:

WB, IHC

Name of antibody:

UBA2

Immunogen:

Synthesized peptide derived from C-terminal of human Uba2.

Full name:

ubiquitin-like modifier activating enzyme 2

Synonyms：

ARX; SAE2; HRIHFB2115

SwissProt:

Q9UBT2

IHC positive control:

Human lung carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

71 kDa

WB Positive control:

293 cells lysates treated with UV (5mins)

WB Recommended dilution:

500-3000