Background:

The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity.

Applications:

ELISA, WB, IHC

Name of antibody:

TXN

Immunogen:

Synthetic peptide of human TXN

Full name:

Thioredoxin

Synonyms：

TRX; TRDX; TRX1

SwissProt:

P10599

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human liver cancer and Human lung cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

12 kDa

WB Positive control:

Hela cells and human liver cancer tissue

WB Recommended dilution:

1000-5000