Background:

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species.

Applications:

WB, IHC, IF

Name of antibody:

TUBA1A

Immunogen:

Synthesized peptide derived from C-terminal of human Tubulin α.

Full name:

tubulin, alpha 1a

Synonyms：

LIS3; TUBA3; B-ALPHA-1

SwissProt:

Q71U36

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

50 kDa

WB Positive control:

MCF7,COLO and HepG2 cells lysates

WB Recommended dilution:

500-3000

IF positive control:

NIH/3T3 cells

IF Recommend dilution:

100-500