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DPYD抗原(重組蛋白)

品牌:紀(jì)寧生物

貨號(hào):JN14448

規(guī)格: 1mg 100ug

聯(lián)系方式:021-54721350

立即詢價(jià) 說明書下載

產(chǎn)品詳情

中文名稱 :DPYD抗原(重組蛋白)

英文名稱 : DPYD Antigen (Recombinant Protein)


別       名 : DHP; DPD; DHPDHASE


儲(chǔ)       存 : 冷凍(-20℃)


相關(guān)類別: 抗原


概述


Full length fusion protein


技術(shù)規(guī)格


Full name:

dihydropyrimidine dehydrogenase

Synonyms:

DHP; DPD; DHPDHASE

Swissprot:

Q12882

Gene Accession:

BC008379

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene.

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