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Background:
This gene encodes an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants
Applications:
ELISA, WB, IHC
Name of antibody:
FUT8
Immunogen:
Synthetic peptide of human FUT8
Full name:
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
SwissProt:
Q9BYC5
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human cervical cancer and Human brain
IHC Recommend dilution:
25-100
WB Predicted band size:
67 kDa
WB Positive control:
LoVo and PC3 cells
WB Recommended dilution:
500-2000