Background:

This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.

Applications:

ELISA, IHC

Name of antibody:

FUS

Immunogen:

Fusion protein of human FUS

Full name:

FUS RNA binding protein

Synonyms：

TLS; ALS6; ETM4; FUS1; POMP75; HNRNPP2

SwissProt:

P35637

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human breast cancer

IHC Recommend dilution:

30-150