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Background: |
Involved in the interconversion between alpha- and beta-L-fucoses. L-Fucose (6-deoxy-L-galactose) exists as alpha-L-fucose (29.5%) and beta-L-fucose (70.5%), the beta-form is metabolized through the salvage pathway. GDP-L-fucose formed either by the de novo or salvage pathways is transported into the endoplasmic reticulum, where it serves as a substrate for N- and O-glycosylations by fucosyltransferases. Fucosylated structures expressed on cell surfaces or secreted in biological fluids are believed to play a critical role in cell-cell adhesion and recognition processes. |
Applications: |
ELISA, IHC |
Name of antibody: |
FUOM |
Immunogen: |
Full length fusion protein |
Full name: |
fucose mutarotase |
Synonyms: |
FUCU; FucM; C10orf125 |
SwissProt: |
A2VDF0 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human breast cancer |
IHC Recommend dilution: |
25-100 |